New UN report outlines ways to prevent next pandemic

As the COVID-19 pandemic continues to take lives and disrupt economies across the world, a new report warns that further outbreaks will emerge unless governments take active measures to prevent other zoonotic diseases from crossing into the human population, and sets out ten recommendations to prevent future pandemics.

The report, Preventing the Next Pandemic: Zoonotic diseases and how to break the chain of transmission, is a joint effort by the United Nations Environment Programme (UNEP) and the International Livestock Research Institute (ILRI).

It identifies seven trends driving the increasing emergence of zoonotic diseases, including increased demand for animal protein; a rise in intense and unsustainable farming; the increased use and exploitation of wildlife; and the climate crisis. The report finds that Africa in particular, which has experienced and responded to a number of zoonotic epidemics including most recently, to Ebola outbreaks, could be a source of important solutions to quell future outbreaks.

“The science is clear that if we keep exploiting wildlife and destroying our ecosystems, then we can expect to see a steady stream of these diseases jumping from animals to humans in the years ahead,” said UNEP Executive Director Inger Andersen. “Pandemics are devastating to our lives and our economies, and as we have seen over the past months, it is the poorest and the most vulnerable who suffer the most. To prevent future outbreaks, we must become much more deliberate about protecting our natural environment.”

A “zoonotic disease” or “zoonosis” is a disease that has passed into the human population from an animal source. COVID-19, which has already caused more than half a million deaths around the world, most likely originated in bats. But COVID-19 is only the latest in a growing number of diseases – including Ebola, MERS, West Nile fever and Rift Valley fever – whose spread from animal hosts into human populations has been intensified by anthropogenic pressures.

Every year, some two million people, mostly in low- and middle-income countries, die from neglected zoonotic diseases. The same outbreaks can cause severe illness, deaths, and productivity losses among livestock populations in the developing world, a major problem that keeps hundreds of millions of small-scale farmers in severe poverty. In the last two decades alone, zoonotic diseases have caused economic losses of more than $100 billion, not including the cost of the COVID-19 pandemic, which is expected to reach $9 trillion over the next few years.

African countries have an opportunity to lead pandemic prevention efforts

Zoonotic diseases are on the rise everywhere on the planet, and African countries – a number of which have successfully managed deadly zoonotic outbreaks – have the potential to leverage this experience to tackle future outbreaks through approaches that incorporate human, animal and environmental health. The continent is home to a large portion of the world’s remaining intact rainforests and other wild lands. Africa is also home to the world’s fastest-growing human population, leading to an increase in encounters between livestock and wildlife and in turn, the risk of zoonotic diseases.

“The situation on the continent today is ripe for intensifying existing zoonotic diseases and facilitating the emergence and spread of new ones,” said ILRI Director General Jimmy Smith. “But with their experiences with Ebola and other emerging diseases, African countries are demonstrating proactive ways to manage disease outbreaks. They are applying, for example, novel risk-based rather than rule-based approaches to disease control, which are best suited to resource-poor settings, and they are joining up human, animal and environment expertise in proactive One Health initiatives.”

The report’s authors identify the One Health approach — which unites public health, veterinary and environmental expertise — as the optimal method for preventing as well as responding to zoonotic disease outbreaks and pandemics.

The report identifies ten practical steps that governments can take to prevent future zoonotic outbreaks: Investing in interdisciplinary approaches, including One Health; Expanding scientific enquiry into zoonotic diseases; Improving cost-benefit analyses of interventions to include full-cost accounting of societal impacts of disease; Raising awareness of zoonotic diseases and strengthening monitoring and regulation practices associated with zoonotic diseases, including food systems.

Others are incentivizing sustainable land management practices and developing alternatives for food security and livelihoods that do not rely on the destruction of habitats and biodiversity; Improving biosecurity and control, identifying key drivers of emerging diseases in animal husbandry and encouraging proven management and zoonotic disease control measures;

Supporting the sustainable management of landscapes and seascapes that enhance sustainable co-existence of agriculture and wildlife; Strengthening capacities among health stakeholders in all countries; and Operationalizing the One Health approach in land-use and sustainable development planning, implementation and monitoring, among other fields.

The report launch comes on World Zoonoses Day, observed by research institutions and nongovernmental entities on 6 July, which commemorates the work of French biologist Louis Pasteur. On 6 July 1885, Pasteur successfully administered the first vaccine against rabies, a zoonotic disease.